In view of the situation of original 5Ni steel welding rod that the steel plate needs to be preheated before welding and the production efficiency is relatively low, OK 92.55 welding rod and NI-C70S welding rod are used for the 5Ni steel welding during the construction of 99 000 m3 Type B tank of Very Large Ethane Carrier (VLEC). After the test research on welding rod performance, cracking resistance, and welding procedure, the results show that: the performance of two kinds of welding rod meet the requirements of the specification, and the cracking resistance is good; when the welding parameters are in a reasonable range, two kinds of welding rod can meet the performance requirements of 5Ni steel welding joints in actual ship construction without preheating steel plates.