In view of proposed three lifting schemes for superstructure overall lifting of a large ship, a finite element analysis on the structure response under the action of dead weight is conducted with MSC.Patran and MSC Nastran, and the obtained superstructure stress and deformation are compared to select the optimal scheme. The results show that the position and number of lifting points and lifting hooks affect the structure stress and deformation. The research conclusion is of strong guidance and reference significance for the design of superstructure overall lifting scheme of large ships.