In order to solve the problem of accurate measurement of thermal cycle parameters of heat-affected zone (HAZ) in submerged arc welding of medium thick plate and high strength steel, a set of multi-channel thermocouple temperature measuring software/hardware system was developed independently in this paper to measure and compare the main thermal cycle parameters of HAZ corresponding to different welding wire combinations (monofilament and cold/hot multi-wire). The analysis results show that, on the one hand, compared with the traditional monofilament submerged arc welding process, the cold and hot multi-wire composite submerged arc welding process can solve the heat-affected zone embrittlement problem caused by the large line energy of submerged arc welding, thus improving the weld microstructure and welding quality. On the other hand, it can also provide the numerical simulation of the temperature field in the welding process of the plate to provide the measured data for the development and optimization of various process parameters in the welding process of the plate, and the weld and heat-affected zone to improve the organizational properties of the necessary theoretical basis for ensuring the quality of the submerged arc welding process of the plate is also of great importance.